有机化学
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赵宝祥
发布时间:2018年09月01日 08:10    作者:化学与化工学院    点击:[]

【个人简介】

  • 姓 名 赵宝祥
    性 别
    出生日期 1959-09-23
    学 历 博士
    职 称 教授  ( 博导 [聘任于2007])
    学术身份
    行政职务
    学术团体兼职
    研究类别 有机化学 ::
    工作单位 有机化学研究所 ::
    电 话 0531-88366425
    传 真
    地 址
    E-mail bxzhao@sdu.edu.cn
  •  

【学习及工作经历】

  • 1978.10-1982.6 大连理工大学化学工程系学习(本科)
    1983.9-1986.6 大连理工大学研究生院精细化工系学习(硕士研究生)
    1986.7-1993.3 山东省化工研究院工作,工程师
    1994.10-1998.3 日本名古屋大学,博士研究生,获得应用化学专业工学博士学位
    1998.3-1999.9 山东大学化学院有机化学研究所,副教授
    1999.10-2000.6 德国柏林工业大学有机化学研究所博士后研究员
    2000.7-今 山东大学化学与化工学院有机化学研究所,教授
    2003.7-2004.6 韩国昌原大学合成化学研究所博士后研究员

【主讲课程】

  • 有机化学 (化学基地班,双语教学)

    有机化学实验,

    综合化学实验

    有机合成新方法(研究生学位必修课)

    合成化学(研究生必修课)

【研究领域和兴趣】

  • 有机合成 荧光探针 药物化学,杂环化学, 化学生物学

【主要论著】

  • 2018年

    1. Miao-Fei Huang, Li-Na Chen, Jun-Ya Ning, Wen-Li Wu, Xiao-Dong He, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A new lipid droplets-targeted fluorescence probe for specific detection of SO2 derivatives in living cells,
    Sensors and Actuators B 261 (2018) 196–202.


    2. Long-Long Xi, Xue-Fei Guo, Chen-Liang Wang, Wen-Li Wu, Miao-Fei Huang, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A near-infrared ratiometric fluorescent probe for rapid and selective detection of hypochlorous acid in aqueous solution and living cells,  
    Sensors and Actuators B 255 (2018) 666–671.


    3. Dong-Peng Li, Xian-Jing Han, Ze-Quan Yan, Yun Cui, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A far-red ratiometric fluorescent probe for SO2 derivatives based on the ESIPT enhanced FRET platform with improved performance,  
    Dyes and Pigments 151 (2018) 95–101.


    4. Li-Jie Zhang Jun-Ya Ning, Jun-Ying Miao, Jin-Ting Liu*, Bao-Xiang Zhao*,
    A new ratiometric fluorescent probe for detecting endogenous HClO in living cells,
    New J. Chem., 2018, 42, 2989--2993.

  • 2017

  • 1. Dong-Peng Li,Zhao-Yang Wang,Hao Su,Jun-Ying Miao* and Bao-Xiang Zhao*

  • Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform
    Chem. Commun.,2017, 53, 577-58.

  • 2. Shi-Li Shen,Xuan Zhao,Xiao-Fan Zhang,Xuan-Li Liu,Hao Wang,Yi-Ying Dai,Jun-Ying Miao and Bao-Xiang Zhao*
    A mitochondria-targeted ratiometric fluorescent probe for hypochlorite and its applications in bioimaging
    J. Mater. Chem. B, 2017, 5,289-295.

    3. Wen-Li Wu, Han-Lin Ma, Miao-Fei Huang,Jun-Ying Miao,Bao-Xiang Zhao*
    Mitochondria-targeted ratiometric fluorescent probe based on FRET for bisulfite
    Sensors and Actuators B 241 (2017) 239–244.

    4. Yan-Ru Zhang, Ying Liu, Xiao Feng, Bao-Xiang Zhao*
    Recent progress in the development of fluorescent probes for the detection of hypochlorous acid
    Sensors and Actuators B 240 (2017) 18–36.

    5. Wen-Li Wu, Xuan Zhao, Long-Long Xi, Miao-Fei Huang, Wen-Hui Zeng, Jun-Ying Miao*, Bao-Xiang Zhao*
    A mitochond ria-targetedfl uorescence probe for ratiometric detection of endogenous hypochlorite in the living cells
    Analytica Chimica Acta 950 (2017) 178-183.

  • 6. Shi-Li Shen, Jun-Ya Ning, Xiao-Fan Zhang, Jun-Ying Miao, Bao-Xiang Zhao*
    Through-bond energy transfer-based ratiometric fluorescent probe for the imaging of HOCl in living cells
    Sensors and Actuators B 244 (2017) 907–91

  • 7. Qiong Yuan, Zhi-Min Zhao, Yan-Ru Zhang, Le Su, Jun-Ying Miao, Bao-Xiang Zhao*
    A lysosome-targeted ratiometric fluorescent probe for detection of hypochlorous acid in living cells
    Sensors and Actuators B 247 (2017) 736–741.

  • 8. Li-Jie Zhang, Zhao-Yang Wang, Jin-Ting Liu, Jun-Ying Miao, Bao-Xiang Zhao*,  
    A rational design of ratiometric fluorescent probes based on new ICT/FRET platform and imaging of endogenous sulfite in living cells,
    Sensors and Actuators B 253 (2017) 19–26.

  • 9. Dong-Peng Li, Zhao-Yang Wang, Jie Cui, Xin Wang, Jun-Ying Miao,Bao-Xiang Zhao*,
    A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells,
    Scientific RepoRts, 7:45294.


  • 2016

  • 1. Dong-Peng Li, Zhao-Yang Wang, Xiang-Jian Cao, Jie Cui, Xin Wang, Hao-Zhong Cui, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A mitochondria-targeted fluorescent probe for ratiometric detection of endogenous sulfur dioxide derivatives in cancer cells,
    Chem. Commun., 52 (2016) 2760--2763.

    2. Xiao Feng, Tao Zhang, Jin-Ting Liu, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria,
    Chem. Commun. 52 (2016) 3131--3134.

    3. Wen-Li Wu,Zhao-Yang Wang, Xi Dai, Jun-Ying Miao & Bao-Xiang Zhao*,
    An effective colorimetric and ratiometric fluorescent probe based FRET with a large Stokes shift for bisulfite.
    Scientific Reports,6:25315 (2016).

    4. Yan-Ru Zhang, Zhi-Min Zhao, Jun-Ying Miao, Bao-Xiang Zhao*,
    A ratiometric fluorescence probe based on a novel FRET platform for imaging endogenous HOCl in the living cells,
    Sensors and Actuators B 229 (2016) 408–413.

    5. Xi Dai, Tao Zhang, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A ratiometric fluorescent probe with DNBS group for biothiols in aqueous solution,
    Sensors and Actuators B 223 (2016) 274-279.


    6. Xi  Dai, Zhao-Yang Wang, Zhi-Fang Du,Jun-Ying Miao,Bao-Xiang Zhao*,
    A simple but effective near-infrared ratiometric fluorescent probe for hydrazine and its application in bioimaging,
    Sensors and Actuators B 232 (2016) 369–374.

    7. Wen-Li Wu, Zhi-Min Zhao,Xi Dai, Le Su, Bao-Xiang Zhao,
    A fast-response colorimetric and fluorescent probe for hypochlorite and its real applications in biological imaging
    Sensors and Actuators B 232 (2016) 390–395

    8. Jie  Cui, Tao Zhang, Yi-Qing Sun, Dong-Peng Li, Jin-Ting Liu, Bao-Xiang Zhao,
    A highly sensitive and selective fluorescent probe for H2S detection with large fluorescence enhancement
    Sensors and Actuators B 232 (2016) 705–711,

    9. Dong-Peng Li, Jin-Feng Zhang, Jie Cui, Xiao-Feng Ma,  Jin-Ting Liu, Jun-Ying Miao,Bao-Xiang Zhao
    A ratiometric fluorescent probe for fast detection of hydrogen sulfide and recognition of biological thiols
    Sensors and Actuators B 234 (2016) 231–238

    10. Li-Jie  Zhang, Zhao-Yang Wang, Xiang-Jian Cao, Jin-Ting Liu, Bao-Xiang Zhao,
    An effective ICT-based and ratiometric fluorescent probe for sensing sulfite
    Sensors and Actuators B 236 (2016) 741–748

    11. Xiang-Jian Cao, Li-Na Chen, Xuan Zhang, Jin-Ting Liu, Ming-Yu Chen,Qiu-Rong Wu, Jun-Ying Miao*, Bao-Xiang Zhao*,
    A NBD-based simple but effective fluorescent pH probe for imaging of lysosomes in living cells,
    Analytica Chimica Acta

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