【主要论著】
Representative publications (from 223 publications): 103. Yanyan Liu, Bing Yan, David A. Winkler, Jianjie Fu, Aiqian Zhang*. Competitive Inhibition Mechanism of Acetylcholinesterase without Catalytic Active Site Interaction: Study on Functionalized C60 Nanoparticles via in vitro and in silico Assays. ACS Applied Materials & Interfaces. 2017. in press. 102. Xue Bai, Fang Liu, Yin Liu, Cong Li, Shenqing Wang, Hongyu Zhou, Wenyi Wang, Hao Zhu, Dave Winkler*, Bing Yan*. Toward A Systematic Exploration of Nano-Bio Interactions. Toxicology and Applied Pharmacology. 2017. in press.
101. Juan Ma; Ruibin Li; Yin Liu; Guangbo Qu; Jing Liu; Wenli Guo; Xinghong Li; Yajun Liu; Tian Xia; Bing Yan;, Sijin Liu*. Carbon nanotubes disrupt iron homeostasis and induce anemia of inflammation through inflammatory pathway as a secondary effect distant to their portal-of-entry. Small. 2017. 100. Jia, Jianbo; Li, Feifei; Zhai, Shumei; Zhou, Hongyu; Liu, Sijin; Jiang, Guibin; Yan, Bing*. Susceptibility of Overweight Mice to Liver Injury as a Result of the ZnO Nanoparticle-Enhanced Liver Deposition of Pb2+. Environmental Science & Technology. 2017. 99. Li, Ye; Yuan, Bing; Yang, Kai; Zhang, Xianren; Yan, Bing; Cao, Dapeng*. Counterintuitive Cooperative Endocytosis of like-charged Nanoparticles in Cellular Internalization: Computer Simulation and Experiment. Nanotechnology. 2016.
98. Long, Yan-Min; Zhao, Xingchen; Clermont, Allen C.; Zhou, Qun fang; Liu, Qian; Feener, Edward P; Yan, Bing; Jiang, Gui bin. Negatively Charged Silver Nanoparticles Cause Retinal Vascular Permeability by Activating Plasma Contact System and Disrupting Adherens Junction. Nanotoxicology 2016 10(4): 501-511.
97. Su, Gaoxing; Zhou, Xiaofei; Zhou, Hongyu; Li, Ye; Zhang, Xianren; Liu, Yin; Cao, Dapeng; Yan, Bing*. Size-Dependent Facilitation of Cancer Cell Targeting by Proteins Adsorbed on Nanoparticles. ACS Applied Materials & Interfaces. 2016, in press.
96. Yongyi Wei, Yang Li, Jianbo Jia, Yiguo Jiang, Bin Zhao, Qiu Zhang*, Bing Yan,* Aggravated Hepatotoxicity Occurs in Aged Mice but not in Young Mice after Oral Exposure to Zinc Oxide Nanoparticles, NanoImpact, 2016, in press.
95. Juan Ma, Ruibin Li, Guangbo Qu, Huiyu Liu, Bing Yan, Tian Xia, Yajun Liu, Sijin Liu, Carbon nanotubes stimulate synovial inflammation through inducing systemic pro-inflammatory cytokines, Nanoscale, 2016, in press.
94. Yongyi Wei and & Bing Yan, NanoProducts in Daily Life –To Know What We Don’t Know, NationalScience Review, 2016, in press.
93. Chuanfeng Teng, Zhiping Wang,&Bing Yan, Fine Particle-induced Birth defects: Impacts of Size, Payload andBeyond, Birth DefectsResearch Part C: Embryo Today: Reviews, 2016,in press.
92. Li, F., Zhou, X., Zhou, H., Jia, J., Li, L., Zhai, S., & Yan, B. Reducing Both Pgp Overexpression and Drug Efflux with Anti-Cancer Gold-Paclitaxel Nanoconjugates. PLoS One, 2016,11(7), e0160042.
91. Jinbao Xiang, Zhuoqi Zhang, Yan Mu, Xianxiu Xu, Sigen Guo, Yongjin Liu, Daniel Russo, Hao Zhu, Bing Yan* and Xu Bai*. Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach. ACS Combinatorial Science. 2016,18(5):230-235
90. Yan Mu, Yongjin Liu, Jinbao Xiang, Qiu Zhang, Shumei Zhai, Daniel P. Russo, Hao Zhu and Xu Bai and Bing Yan*. From fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin polymerization inhibitor. Cell Death and Disease. 2016, 7: e2143
89. Daniel J Klionsky*... Bing Yan, etc.al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016, 12(1): 1-222.
88. Peifu Jiao,Mario Otto, Qiaohong Geng, Chencan Li, Faming Li, Elizabeth R. Butch, Scott E. Snyder, Hongyu Zhoua* and Bing Yan*.Enhancing both CT imaging and natural killer cell-mediated cancer cell killing by a GD2-targeting nanoconstruct. Journal of Materials Chemistry B, 2016, Vol 4, 513-520.
87. Yi Zhang, Yabin Wang, Aijuan Liu, Sherry Li Xu, Bin Zhao, Yi Zhang, Hanfa Zou, Wenyi Wang,Hao Zhu and Bing Yan*. Modulation of Carbon Nanotube's Perturbation to the Metabolic Activity of CYP3A4 in the Liver. Advanced Functional Materials, 2016, Vol 26, 980. JOURNAL COVER
86. Fourches, Denis; Pu, Dongqiuye; Li, Liwen; Zhou, Hongyu; Mu, Qingxin; Su, Gaoxing; Yan, Bing*; and Tropsha, Alexander*. Computer-Aided Design of Carbon Nanotubes with the Desired Bioactivity and Safety Profiles, Nanotoxicology, 2016 10(3):374-383.
85. Yanyan Liu, David A. Winkler*, V. Chandana Epa, Bin Zhang, Bing Yan*,Probing Enzyme-Nanoparticle Interactions using Combinatorial Gold Nanoparticle Libraries.Nano Research. 2015, 8(4): 1293–1308
84. Tu C. Le, Bing Yan,, and David A. Winkler. Robust Prediction of Personalized Cell Recognition from a Cancer Population by a Dual Targeting Nanoparticle Library", Advanced Functional Materials, 2015, Vol 25, 6927-6935.
83. Guangshu Zhai, Sarah Gutowski, Katherine Walters, Bing Yan, Jerald Schnoor. Charge, Size and Celluar Selectivity for Multi-wall Carbon Nanotubes by Maize and Soybean. Environmental Science & Technology. 2015 Jun 16;49(12):7380-90.
82. Shuhuan Li, Shumei Zhai, Yin Liu, Hongyu Zhou, Jinmei Wu, Qing Jiao, Bin Zhang, Hao Zhu*, Bing Yan**. Experimental Modulation and Computational Model of Nano-Hydrophobicity. Biomaterials. 2015, Vol 52, P312-317.
81. Zhiping Wang, Chunhui Li, Yan Mu, Zhang Lin, Anji Yi, Qiu Zhang, Bing Yan*. Nanoadduct Relieves: Alleviation of Developmental Toxicity of Cr(VI) Due to Its Spontaneous Adsorption to Mg(OH)2 Nanoflakes. Journal of hazardous materials. 2015, Vol 287, P296-305.
80. Yin Liu, Fei Li, Ling Wu, Wenyi Wang, Hao Zhu, Qiu Zhang, Hongyu Zhou,Bing Yan*.Improving Both Aqueous Solubility and Anti-Cancer Activity by Assessing Progressive Lead Optimization Libraries. Bioorganic & Medicinal Chemistry Letters. 2015, Vol 25, P1971-1975.
79. Chengke Zhang, Shumei Zhai, Ling Wu, Yuhong Bai, Jianbo Jia, Yi Zhang,Bin Zhang, Bing Yan*, Induction of Size-Dependent Breakdown of Blood-Milk Barrier in Lactating Mice by TiO2 Nanoparticles. PLOS ONE. 2015, 10(4): e0122591.
78. Yan Mu, Yin Liu, Liwen Li, Cong Tian, Hongyu Zhou, Qiu Zhang*, Bing Yan*, The Novel Tubulin Polymerization Inhibitor MHPT Exhibits Selective Anti-tumor Activity against Rhabdomyosarcoma in vitro and in vivo. PLOS ONE. 2015, 10(3): e0121806.
77. Mu QX, Jiang GBi, Chen LX, Zhou HY, Fourches, Denis, Tropsha, Alexander, Yan B*, Chemical Basis of Interactions Between Engineered Nanoparticles and Biological Systems. Chemical Reviews, 2014; 114(15):7740-7781.
76. Zhang Y, Bai YHi, Jian JB, Gao NN, Li Y, Zhang RN, Jiang GB, Yan B*, Perturbation of Physiological Systems by Nanoparticles. Chemical Society Review, 2014, 43, 3762-3809.
75. Wu L, Zhang CK, Cui XH, Zhai SM, Liu Y, Li CL, Zhu H, Qu GB, Jiang GB, Yan B *, Tuning Cell Autophagy by Diversifying Carbon Nanotube’s Surface Chemistry.ACS Nano, 2014 Mar25; 8(3):2087-99.
74. Zhang CK, Zhai SM, Li XE, Zhang Q, Wu L, Liu Y, Jiang CJ, Zhou HY, Li F, ZhangSS, Su GX, Zhang B, Yan B.* Synergistic Action by Multi-targeting Compounds Produces a Potent Compound Combination for Human NSCLC both in vitro and in vivo. Cell Death & Disease, 2014 Mar. 20, 5: 1138.
73. Li LW, Liu Y, Zhang Q, Zhou HY, Zhang Y, Yan B*. Comparison of Microtubule Damage-Triggered Cancer Cell Survival after Turning Kinase Dyrk1BOn and Off.ACS Chemical Biology, 2014 Mar 21, 9(3):731-42.
72. Zhang RN, Pan XH, Li F, Lin Z, Zhai SM, Mu QX, Liu JF, Qu GB, Jiang GB, Yan B.*Cell Rescue by Nano-Sequestration: Reduced Cytotoxicity of An EnvironmentalRemediation Residue, Mg(OH)2 Nanoflake/Cr(VI) Adduct. Environmental Science & Technology, 2014 Feb 4, 48(3): 1984-92.
71. Wang YQ, Yan B, Chen LX. SERS Tags: Novel Optical Nanoprobes for Bioanalysis. Chemical Reviews, 2013,113(3), 1391-1428.
70. Zhang Q, Zhai SM, Li LW, Li XE, Zhou HY, Liu AF, Su GX, Mu QX, Du YH, Yan B.*Anti-tumor selectivity of a novel Tubulin and HSP90 dual-targeting inhibitor innon-small cell lung cancer models. Biochemical Pharmacology, 2013, 86(3): 351-360.
69. Yan B. Therapy at the Nano Dimension. Current Pharmaceutical Design, 2013,Vol. 19.
68. Zhang CK, Zhang Q, Zhang Y, Yan B.* Toward a Better Understanding of Pharmacokinetics of Nanomaterials. Current Pharmaceutical Design, 2013, 19(37): 6667-6680
67. Liu AJ, Zhai SM, Zhang B, Yan B.* Analytical Strategies for Real-Time andNon-Invasive Tracking of Carbon Nanomaterials in vivo.Trendsin Analytical Chemistry, 2013,48, 1-13.
66. Zhang Y, Tekobo S, Tu Y, Zhou QF, Jin XL, Dergunov S,Pinkhassik E, Yan B.* Permission to Enter Cell by Shape: Nanodisk vs.Nanosphere. ACS Applied Materials & Interfaces, 2012, 4(8), 4099-4105. Highlighted by Chemical &Engineering News, 2012, Aug. 7.
65. Zhang B, Pai Panandiker AS, Yan B.* A Nano-CombinatorialApproach to Developing Cancer Diagnostics. Nanomedicine (U.K.),2012, 7(7), 937-940.
64. Zhang Y, Mu QX, Zhou HY, Karen Vrijens, Martine F. Roussel, Jiang GB and Yan B* Binding of Carbon Nanotube to BMPReceptor 2 Enhances Cell Differentiation and Inhibits Apoptosis via RegulatingbHLH Transcription Factors. Cell Death and Disease, 2012, 3, e308.
63. Mu QX, Su GX, Li LW, Gilbertson B, Yu L, Zhang Q, Sun Y-P, YanB.* Size-Dependent Cell Uptake of Protein-Coated Graphene Oxide Nanosheets. ACS Applied Materials & Interfaces, 2012, 4(4), 2259-2266.
62. Zhou HY, Su GX, Jiao PF, Yan B.* Accelerating the Multifunctionalization of Theranostic Nanoparticles Using a Multicomponent Reaction. Chemistry - A European Journal, 2012,18(18), 5501-5505.
61. Su GX, Zhou HY, Mu QX, Zhang Y, Li LW, Jiao PF, Jiang GB, YanB.* Effective Surface Charge Density Determines the Electrostatic Attraction between Nanoparticles and Cells. Journal of Physical Chemistry C, 2012, 116(8),4993-4998.
60. Jiao PF, Zhou HY, Otto M, Mu QX, Li LW, Su GX, Zhang Y, Butch E, Snyder S,Jiang GB, Yan B.* Leading Neuroblastoma Cells to Die by Multiple Premeditated Attacks from a Multifunctionalized Nanoconstruct. Journal of American Chemistry Society, 2011, 133(35), 13918-13921.
59. Gao NN, Zhang Q, Mu QX, Bai, YH, Li LW, Zhou HY, Butch, E, Powell, T, Snyder,S, Jiang, G, Yan, B*, Steering Carbon Nanotubes to Scavenger ReceptorRecognition by Nanotube Surface Chemistry Modification Partially Alleviates NFκB Activation and Reduces Its Immunotoxicity. ACS Nano, 2011, 5(6), 4581-4591.
58. Wang F, Zhai SM, Liu XJ, Li LW, Wu S, Dou QP*, Yan, B.* A Novel Dithicarbamate Analogue with Potentially Decreased ALDH Inhibition has Copper-Depentent Proteasome-Inhibitory and Apoptosis-Inducing Activity in Human Breast Cancer Cells. Cancer Letters, 2011, 300(1), 87-95.
57. Li X, Zhou HY, Yang L, Du GQ, Pai-Panandiker A, Huang XF, and Yan B.*Enhancement of Cell Recognition in vitro by Dual-Ligand Cancer Targeting Gold Naoparticles. Biomaterials, 2011, 232, 2540-2545.
56. Jiao PF, Zhou HY, Chen L, Yan B.* Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy. Current Medicinal Chemistry, 2011,18, 2086-2102.
55. Yan B. Impacts of Nanotechnology on Medicinal Chemistry and Drug Discovery. Current Medicinal Chemistry, 2011, 18(14), 2044.
54. Wu L and Yan B.* Discovery of Small Molecules that Target Autophagy for Cancer Treatment. Current Medicinal Chemistry, 2011, 18, 1866-1873.
53. Zhou QF, Dergunov SA, Zhang Y, Li X, Mu QX, Zhang Q, Jiang GB, Pinkhassik F,Yan B.* Safety profile and cellular uptake of biotemplated nanocapsules withnanometer-thin walls. Nanoscale, 2011,136,872-877.
52. Li LW, Zhang Q, Liu AF, Li, XE,Zhou HY,Liu Y, Yan B.* Proteome Interrogation Using Nanoprobes to Identify Targets of aCancer-killing Molecule. Journal of American Chemistry Society, 2011, 133(18),6886-6889.
51. Zhou HY, Jiao PF, Yang L, Li X, Yan B.* Enhancing Cell Recognition by Scrutinizing Cell Surfaces with a Nanoparticle Array. Journal of American Chemistry Society, 2010, 133(4),680-682.
50. Bai YH, Zhang Y, Zhang JP, Mu QX, Zhang WD, Butch E, Snyder S,Yan B.* Repeated carbon nanotube administrations in male mice cause reversibletestis damage without affecting fertility. Nature Nanotechnology, 2010, 5(9),683-689.
Highlighted by Nature China, RSC Chemistry World, NanoWerk, Institute of Nanotechnology, Meridian Institute, Softpedia, 北京科技报，香港文汇报 and more than 50 websites.
49. Zhang Y, Bai Y, Yan B.* Functionalized Carbon Nanotubes for Potential Medicinal Applications. Drug Discovery Today, 2010, 15(11-12), 428-435.
48. Yan B, Zhang B. Analyticalmethods in combinatorial chemistry, Second Edition by Francis and Taylor Group, 2010
47. Mu QX, Yang L, Davis JC, Vankayala R, Hwang KC, Zhao JC, YanB.* Biocompatibility of Polymer Grafted Core/Shell Iron/Carbon Nanoparticles. Biomaterials, 2010, 31(19), 5083-5090.
46. Wang F, Jiao PF, Qi MH, Frezza, M., Dou QP.*, Yan, B.* Turning Tumor-Promoting Copper into anAnti-Cancer Weapon via High-Throughput chemistry. Current Medicinal Chemistry, 2010,17(25), 2685-2698.
45. Zhang Q, Zhou, H.Y., Zhai,S.M., Yan, B.* Natural Product–Inspired Synthesis of Thiazolidine andThiazolidinone Compounds and Their Anticancer Activities.Current Medicinal Chemistry, 2010, 16(16), 1826-1842.
44. Zhai SM, Yang L., Cui QZC., Sun Y, Dou, Q.P.*, Yan, B.* Tumor Cellular Proteasome Inhibition and Growth Suppression by 8-Hydroxylquinoline and Clioquinol Requires Their Capabilities to Bind Copper and Transport Copper into Cells. Journal of Biological Inorganic Chemistry, 2010, 15(2), 259-269.
43. Mu QX, Broughton DL, Yan B.*Endosomal leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake. Nano Letters, 2009, 9(12), 4370-4375.
42. Mu QX, Du GQ, Chen, TS, Zhang B, Yan B* Suppression of Human Bone Mophorgenetic Protein (BMP) Signaling by Carboxylated Single-Walled Carbon Nanotubes. ACS Nano, 2009,3,(5), 1139-1144.
41. Zhang B, Xing YH, Zhou HY, Li ZW, Mu QX, Yan B.* Functionalized Carbon Nanotubes Specifically Bind to Chymotrypsin Catalytic Site and Regulate its Enzymatic Function. Nano Letters, 2009,9(6), 2280–2284.
40. Yan B, and Czarnik, AW, Series Editors, Critical Review in Combinatorial Chemistry Volume 5. Chen, T. High-Throughput Screening Technologies by Francis and Taylor Group, 2009
39. Qu GB, Bai YH, Zhang Y, Jia Q, Zhang WD, Yan B*, The effect of multiwalled carbon nanotube agglomeration on theiraccumulation in and damage to organs in mice. Carbon, 2009,47(8), 2060-2069.
38. Mu QX, Li, Li X, Sanjay R. Mishra, Zhang B, Si ZK, Yang L, Jiang W, Yan B*. Characterization of Protein Clusters of Diverse Magnetic Nanoparticles and Their Dynamic Interactions with Human Cells. Journal of Physical Chemistry C, 2009, 113 (14),5390-5395.
37. Du FF, Zhou HY, Chen LX, Zhang B, Yan B*, Structure Elucidation of Nanoparticle-Bound Organic Molecules by 1HNMR. Trends in Analytical Chemistry, 2009,28(1),88-95.
36. Zhou HY, Du FF, Li X, Zhang B, Li W, Yan B.* Characterization of Organic Molecules Attached to Gold Nanoparticle Surface Using High Resolution Magic Angle Spinning 1H NMR. Journal of Physical Chemistry C, 2008, 112 (49) 19360-19366.
35. Zhou HY, Mu QX, Gao NN, Liu A, Xing Y, Gao SL, Zhang Q, Qu GB, Chen Y, Liu G, Zhang B, Yan B*, A Nano-Combinatorial Library Strategy for the Discovery of Nanotubes with Reduced Protein-Binding, Cytotoxicity and Immune Response, Nano Letters, 2008,8 (3), 859-865.
34. Zhou HY, Wu S, Zhai SM, Liu A, Sun Y, Li R, Zhang Y, Ekins, S., Swaan, PW, Fang B, Zhang B, Yan B* Design, Synthesis, Cytoselective Toxicity, Structure-Activity Relationships, and Pharmacophore of Thiazolidinone Derivatives Targeting Drug-Resistant Lung Cancer Cells,” Journal of Medicinal Chemistry, 2008, 51,1242-1251.
Highlighted by Drug Discovery Today, 13, 1107-1108, 2008
33. Yan, B. and A. W. Czarnik, Series Editors, Critical Review in Combinatorial Chemistry Volume 3. Tushar A. Kshirsagar Editor, High-Throughput Lead Optimization in Drug Discovery. by Francis and Taylor Group, 2008
32. Yan, B. and A. W. Czarnik, Series Editors, Critical Review in Combinatorial Chemistry Volume 4. Wang, P. High-Throughput Analysis in Pharmaceutical Industry byFrancis and Taylor Group, 2008
31. Mu, Q.; Liu, W.; Xing, Y.; Zhou, H.; Li, Z.; Zhang, Y.; Ji, L.;Wang, F.; Si, Z.; Zhang, B.; Yan, B.* Protein Binding by Functionalized Multiwalled Carbon Nanotubes Is Governed by the Surface Chemistry of Both Parties and the Nanotube Diameter, Journal of Physical Chemistry C, 2008, 112 (9), 3300-3307.
30. Yan, B.* Zhao,J., Leopold, K., Zhang, B.,Jiang, G. The Structure Dependent Response of Chemiluminescence Nitrogen Detector (CLND) for Organic Compounds with Adjacent Nitrogen Atoms Connected by a Single Bond, Analytical Chemistry, 2007, 79 (2) 718-726.
29. Yan, B. and A.W. Czarnik, Series Editors, Critical Review in Combinatorial Chemistry Volume 1. Radislav A. Potyrailo, Wilhelm Maier. Editors, Combinatorial and High-Throughput Discovery and Optimization of Catalysts and Materials by Francis and Taylor Group, 2005.
28. Yan, B. and A. W. Czarnik, Series Editors, Critical Review in Combinatorial Chemistry Volume 2. Armen M. Boldi, Editor, Combinatorial Synthesis of NaturalProduct Based Libraries. by Francis and Taylor Group, 2005
27. Yan, B. Editor, Chemical Analysis – A Series ofMonographs on Analytical Chemistry and Its Applications Volume 163 “Analytical and purification methods in Combinatorial Chemistry” by John Wiley and Sons, Inc., 2003
Highlighted by: Journal of Natural Products, 2004, Vol. 67, No. 6, 1076. Angew.Chem. Int. Ed. 2004, 43, 4552 – 4553. Drug Development And Industrial Pharmacy,2004, Vol. 30, No. 7, p. 793.
26. Yan, B.* Single bead analysis in combinatorial chemistry, Current Opinion in Chemical Biology, 2002, 6, 328-332.
25. Fang,L., Demee, M., Sierra, T., Kshirsagar, T., Celebi, A., Yan, B.* Kinetic Studyof Amine Cleavage Reactions of Various Resin-Bound Thiophenol Esters from Marshall Linker, Journal of Combinatorial Chemistry, 2002, 4, 362-368.
24. Yan, B. and Czarnik, A.Editors, Optimization of solid-phase combinatorial synthesis by Marcel Dekker, New York, 2001
Highlighted by J. AM. CHEM. SOC. 9 VOL. 124, NO. 26, 2002 7875
23. Gremlich, H. U. and Yan, B. Editors, Biological FTIR and Raman Spectroscopy by Marcel Dekker, New York, 2000
Highlighted by J. A. C. S., Vol. 123, No. 42, 2001 10427
22. Yan, B.*, Nguyen, N., Liu, L., Holland, G., Raju, B. Kinetic Comparison of Trifluoroacetic Acid Cleavage Reactions of Resin-Bound Carbamates, Ureas, Secondary Amides, and Sulfonamides from Benzyl-, Benzhydryl-, and Indole-Based Linkers, Journal of Combinatorial Chemistry, 2000, 2(1) 66-74.
21. Yan, B., Analytical methods incombinatorial chemistry by CRC Press (former Technomics), 1999
Highlighted by Journal of Medicinal Chemistry, 2001, Vol. 44, No. 20,3334.
20. Yan, B.*, Liu, L., Astor, C. A., Tang, Q. Determination of the Absolute Amount of Resin-Bound Hydroxyl or Carboxyl Groups for the Optimization of Solid-Phase Combinatorialand Parallel Organic Synthesis, Analyical Chemistry, 1999, 71(20) 4564-4571.
19. Yan,B.*, Martin,P. C., Lee, J. Single Bead Fluorescence Microspectroscopy: Detection of Self-Quenching in Fluorescence-Labeled Resin Beads, Journal of Combinatorial Chemistry, 1999, 1, 78-81.
18. Yan,B.*, Gremlich, H.-U., Moss, S., Coppola,G. M., Sun, Q., Liu, L. A comparison of various FTIR and FT raman methods: applications in the reaction optimization stage of combinatorial chemistry, Journal of Combinatorial Chemistry, 1999, 1, 46-54.
17. Yan, B.*, Monitoring the progress and the yield of solid-phase organic reactions directly on resin supports, Accounts of Chemical Research, 1998, 31, 621-630.
16. Yan, B.*, Jewell, Jr. C. F., Myers, S. W., Quantitatively monitoring of solid-phase organic synthesis by combustion elemental analysis, Tetrahedron, 1998, 54, 11755-11766.
15. Li, W. and Yan, B.*, Effects of Polymer Supports on the Kinetics of Solid-Phase Organic Reactions: A Comparison of Polystyrene- and Tenta Gel-Based Resins,Journal of Organic Chemistry, 1998, 63,4092-4097.
14. Sun, Q. and Yan, B.*, Single bead IR monitoring a novel benzimidazolesynthesis. Bioorganic Medicinal Chemistry Letters, 1998, 8, 361-364.
13. Yan,B.* and Sun, Q., Crucial factors regulating site-interactions in resin supports determined by single bead IR,” Journal of Organic Chemistry, 1998, 63, 55-58.
12. Yan,B.* and Li, W., Rapid fluorescence determination of the absolute amount of aldehyde and ketone groups on resin supports, Journal of Organic Chemistry, 1997, 62,9354-9357.
11. Yan,B., Spudich, E. N., Sheves, M. and Spudich, J. L., Complexation of the signal transducing protein HtrI tosensory rhodopsin I and its effect on thermodynamics of signaling statedeactivation, Journal of Physical Chemistry B, 1997, 101, 109-113.
10. Yan,B.*, Sun, Q., Wareing, J. R. and Jewell, C. F. Real-time Monitoring of the Catalytic Oxidation of Alcohols on Resin Supports by Single Bead FTIR Microspectroscopy, Journal of Organic Chemistry, 1996, 61,8765-8770.
9. Yan,B.*, Fell, J. B. and Kumaravel, G. Progression of organic reactions on resin supports monitored by single bead FTIR microspectroscopy, Journal of Organic Chemistry, 1996, 61, 7467-7472.
Highlighted by CHEMTRACTS-ORGANIC CHEMISTRY 10:822-827, 1997.
8. Yan,B.*, Spudich, J. L., Mazur, P., Vunnam, S., Derguini, F. and Nakanishi, K., Spectral tuning in bacteriorhodopsin in the absence of counterion and coplanarization effects, Journal of Biological Chemistry, 1995, 270, 29668-29670.
7. Yan,B.*, Kumaravel, G., Anjaria, H., Wu, A., Petter, R. C., Jewell, C. F. and Wareing, J., Infrared spectrum of a single resin bead for real-time monitoring of solid-phase reactions, Journal of Organic Chemistry, 1995, 60,5736-5738.
Selected asBio-Rad Application Note in 1996.Received 145 citations.
6. Yan,B., Xie, A., Nienhaus, G. U., Katsuta, Y. & Spudich, J. L. Steric con-straints in the retinal binding pocket ofsensory rhodopsin I, Biochemistry, 1993, 32, 10224-10232.
5. Ratto,G.M., D.W.Robinson, B.Yan & P.A.Mc Naughton, Develop-ment of the light response in neonatal mammalianrods, Nature (Lon-don), 1991,351, 654-657.
4. Yan,B., K.Nakanishi & J.L.Spudich., Mechanism of activa-tion of sen-sory rho-dopsin I: evidence for a steric trigger, Proc. Nat. Acad. Sci. U.S.A. 1991, 88, 9412-9416.
3. Yan, B., T.Takahashi, Johnson, R. & J.L.Spudich., Identifica-tion of sig-naling states of a sensoryreceptor by modulation of lifetimes of stim-ulus-in-duced conformations: thecase of sensory rhodopsin II, Biochemistry, 1991, 30,10686-10692.
2. Yan,B., T.Takahashi, D.A.McCain, V.J.Rao, K.Nakanishi & J.L.Spudich., Ef-fects of modifications of the retinalb-ionone ring on archaebacterial sensory rhodopsin I,Biophysical Journal, 1990, 57, 477-483.
1. Yan,B., T.Takahashi, R.Johnson, F.Derguini, K.Nakanishi, J.L.Spudich. All-trans/13-cis isomerization of retinal is required for phototaxis signaling by sensory rhodopsins in halobacterium halobium, Biophysical Journal, 1990,57, 807-814.
|